| Theme | Prognosis of Liver Diseases | |
|---|---|---|
| Title | Prognosis of Patients with Cirrhosis due to Hepatitis Virus -- Hepatitis B and Hepatitis C | |
| Publish Date | 1997/10 | |
| Author | Naoaki Hayashi | Division of Medicine, Institute of Gastroenterology, Tokyo Women's Medical College |
| [ Summary ] | We studied 16 reports concerning the prognosis associated with cirrhosis after 1987. Although the median 5-year survival rate of cirrhosis patients was 62% regardless of the etiology, it improved from 55% before 1989 to 70% after 1990. We compared the survival rate between cirrhosis due to hepatitis B (type B) and cirrhosis due to hepatitis C(type C). Although there was no difference up to 10 years, the survival rate with type B cirrhosis did not decrease significantly whereas that associated with type C cirrhosis continued to decrease as a constant rate after 10 years. This tendency was also seen in the developement rate of hepatocellular carcinoma (HCC), and it is speculated that HCC develops from type C cirrhosis at a constant rate even after 10 years. The prognosis of cirrhotic patients, who are positive for both hepatitis B virus and hepatitis C virus, is worse than that of those who are positive for only one of these viral genomes although there are only a few reports concerning this issue. |
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