| Theme | Lifestyle-related diseases and fracture risk | |
|---|---|---|
| Title | Bone metabolism in diabetes, dyslipidemia, hypertension, and the metabolic syndrome | |
| Publish Date | 2010/01 | |
| Author | Toru Yamaguchi | Internal Medicine 1, Shimane University Faculty of Medicine |
| [ Summary ] | Recent experiments with osteocalcin-deficient mice and the mevalonate pathway in cultured cells have indicated that there is a common pathogenesis between bone metabolism and glucose/lipid metabolism. Clinical studies also suggest that type 2 diabetes, dyslipidemia and hypertension may have detrimental effects on bone, while metabolic syndrome may have a beneficial effect on it. | |