The Japanese Journal of Clinical Dialysis Vol.35 No.2(1)

Theme Electrolyte and acid-base disorders in dialysis patients
Title Management of electrolytes in patients on dialysis
Publish Date 2019/02
Author Takahiro Kamiyama Department of Blood Purification, Tokyo Women's Medical University
Author Norio Hanafusa Department of Blood Purification, Tokyo Women's Medical University
[ Summary ] Plasma electrolytes are involved in the regulation of osmotic pressure as well as activities of nerve cells and muscle cells. Thus, maintaining proper concentrations of electrolytes is crucial for maintaining homeostasis in the body. Kidneys play a major role in controlling the concentration of major electrolytes such as sodium (Na), potassium (K), calcium (Ca), phosphorus (P), magnesium (Mg), and bicarbonate. Therefore, in dialysis patients with highly impaired renal function, we should replace kidney function in terms of electrolytes by dialysis through diffusion and ultrafiltration. Since abnormal electrolyte concentrations can also affect the long-term prognosis of patients on dialysis, the mechanisms involved in the balance of each electrolyte, distribution in the body, and regulation of electrolyte concentrations must be better understood.
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