| Theme | Infectious diseases of the intestine | |
|---|---|---|
| Title | Significance of intestinal biopsy for intestinal infection | |
| Publish Date | 2019/04 | |
| Author | Minako Fujiwara | Department of Health Sciences, School of Medicine, Kyushu University / Department of Anatomic Pathology, Graduated School of Medical Sciences, Kyushu University |
| Author | Yoshifumi Hori | Department of Anatomic Pathology, Graduated School of Medical Sciences, Kyushu University |
| Author | Yutaka Koga | Department of Anatomic Pathology, Graduated School of Medical Sciences, Kyushu University |
| Author | Yoshinao Oda | Department of Anatomic Pathology, Graduated School of Medical Sciences, Kyushu University |
| [ Summary ] | This paper explains special histological findings which are recognized in intestinal biopsy specimens of infectious enterocolitis. Neutrophilic infiltration and hemorrhage in the mucosa are prominent in Campylobacter enteritis rather than in ulcerative colitis. As for Yersinia enteritis, large-sized epithelioid cell granuloma with central necrosis, neutrophilic infiltration, and abscess formation is seen in lymphoid aggregates of the mucosa. In Crohn's disease, these findings are not seen. Aggregates of macrophages filled up with many acid fast bacilli are characteristic for atypical mycobacteriosis. The biopsy specimen of intestinal spirochetosis shows basophilic brush border-like structures on the surface of the mucosa of the large intestine. As for diagnosis of amoebic colitis, Entamoeba historica needs to be proved by necrotic slough of biopsy specimens, which are highlighted by PAS stains and phagocyte erythlocytes. In this way, biopsy specimens are useful in diagnosis of some infectious enterocolitis. | |