| Theme |
Endocrinological control of bone metabolism |
| Title |
Functional cross-talk between bone and adipose tissue |
| Author |
Toru Fukuda |
Department of Administrative Nutrition, Tokyo Seiei College |
| [ Summary ] |
Bone homeostasis is maintained by bone formation and resorption. The traditional view of bone metabolism as a primarily endocrine regulation has been recently expanded following the identification of the nervous and vascular systems controlling bone metabolism. Since the discovery of leptin in 1994, adipose tissue has been considered as an endocrine organ. The identification that leptin controls bone metabolism through the nervous system opened a new field in bone biology. Based on recent findings, bone-adipose tissue cross-talk has been noted. |