腎と骨代謝 Vol.29 No.4(6)


特集名 骨折予防のための栄養と運動
題名 慢性腎臓病患者における運動療法
発刊年月 2016年 10月
著者 上月 正博 東北大学大学院医学系研究科機能医科学講座内部障害学分野
【 要旨 】 慢性腎臓病(CKD)患者においては,サルコぺニア・フレイルの頻度が高い.また,CKDの病態そのものがサルコぺニア・フレイルの発症に関与している.CKD患者に対する腎臓リハビリテーション(腎臓リハ)の中核的役割を担う運動療法は,透析患者の運動耐容能改善,PEW改善,蛋白異化抑制,QOL改善などをもたらす.最近,保存期CKD患者に運動療法を行うことで腎機能が改善するという報告が相次ぎ,保存期CKD患者の透析導入を先延ばしすることができる可能性が高い.平成23年に日本腎臓リハビリテーション学会が設立され,平成28年度診療報酬改定では,腎不全期患者指導加算が設定された.今後,CKD2期以上のCKD患者や透析患者でも運動療法のエビデンスをさらに強固にして,適応拡大や増点をめざす必要がある.CKD患者における腎臓リハのさらなる発展が期待される.
Theme Nutrition and exercise for the fracture prevention
Title Exercise therapy for chronic kidney disease patients
Author Masahiro Kohzuki Department of Internal Medicine and Rehabilitation Science, Tohoku University Graduate School of Medicine
[ Summary ] Chronic kidney disease (CKD) is a worldwide public health issue. This review focuses on the importance and efficacy of renal rehabilitation (RR) for CKD patients. A recent systematic review and meta-analysis of randomized controlled trials reported that exercise-based RR improved aerobic capacity, muscular functioning, cardiovascular function, walking capacity, and health-related quality of life in CKD patients receiving HD. Moreover, exercise training may provide renal protective effects for pre-HD CKD patients. Exercise therapy can be an effective clinical strategy to improve renal function and lower need for renal replacement therapies such as HD or renal transplants in pre-HD CKD patients. The Japanese Association of Renal Rehabilitation was established in 2011 to evaluate and promote RR. A recent decision by the Ministry of Health, Labor and Welfare Japan is to extend RR partial coverage to pre-HD CKD stage 4 patients for the first time anywhere in the world in 2016. Future randomized controlled trials should focus more on the effects of exercise training and rehabilitation programs since these subjects and exercise types have not been studied as fully as cardiovascular exercise.
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