腎と骨代謝 Vol.29 No.1(10)


特集名 歯の細胞生物学
題名 全身疾患と歯周病
発刊年月 2016年 01月
著者 石原 裕一 松本歯科大学歯科保存学講座
著者 吉成 伸夫 松本歯科大学歯科保存学講座
【 要旨 】 歯周病と全身疾患との相互関係を構築する研究分野は,ペリオドンタルメディシン(periodontal medicine)と総称され,一つの学問体系を確立するに至った.現在まで肥満,糖尿病,心臓血管疾患,骨粗鬆症,誤嚥性肺炎,早産・低体重児出産などと歯周病との関係が報告され,20年になろうとしている.さまざまなエビデンスが提供されるとともに,近年では新たに悪性腫瘍やアルツハイマー病といった老年病との関連も登場し,研究領域の広がりをみせると同時に,若干の混乱も生じている.そこで,本稿では歯周病と腎臓疾患との関連を含めたペリオドンタルメディシンの現状整理を行い,解説する.
Theme Cell biology of tooth
Title Systemic diseases and periodontal disease
Author Yuichi Ishihara Departments of Operative Dentistry, Endodontology, and Periodontology, School of Dentistry, Matsamoto Dental University
Author Nobuo Yoshinari Departments of Operative Dentistry, Endodontology, and Periodontology, School of Dentistry, Matsamoto Dental University
[ Summary ] Periodontal medicine is a research field that focuses on the relationship between periodontal disease and systemic diseases and has led to the establishment of one of the academic systems. The relationships between periodontal disease and obesity, diabetes mellitus, cardiovascular disease, osteoporosis, aspiration pneumonia, premature birth, and low birth weight have been reported over 20 years. In recent years, a variety of evidences has been obtained regarding new associations between periodontitis and malignant tumors and geriatric diseases, such as Alzheimer's disease. This research area has shown progress ; however, there are also some controversies. Therefore, this review discusses the status quo in periodontal medicine, including the relationship between periodontal disease and kidney disease.
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