| Theme |
Regulation, disease states and drug targets of kidney tubular transporters -- Topics |
| Title |
Inherited tubular transport disorders : topics |
| Author |
Ken-ichi Miyamoto |
Department of Molecular Nutrition, Institution of Health Biosciences, The University of Tokushima Graduate School |
| [ Summary ] |
Inherited tubular transport disorders comprise a group of diseases which lead to profound derangement of the homeostasis of electrolytes, minerals, and organic solutes. Elucidating the molecular basis for these generally rare disorders has provided important insights into disease pathogenesis as well as the complexities of normal renal transport physiology. This review focuses on the clinical features and recent molecular advances associated with mineral, glucose, uric acid and sodium transporter disorders. |