| Theme |
Approach for sarcopenia and frailty in chronic kidney disease |
| Title |
Sarcopenia and frailty in dialysis patients |
| Author |
Miho Nagai |
Physician, Student and Researcher Support Center, Tokyo Medical University / Department of Nephrology, Tokyo Medical University |
| Author |
Yoshihiko Kanno |
Department of Nephrology, Tokyo Medical University |
| [ Summary ] |
Dialysis patients tend to suffer from catabolic states due to complex factors in the pathogenesis of renal failure and dialysis treatment. Further, sarcopenia and frailty are often associated with aging in dialysis patients, and may contribute to poor quality of life and lack of long term survival. Skeletal muscle mass is regulated by a balance between muscle synthesis and catabolism. Supplement of energy and ensured protein intake, especially of branched-chain amino acids in addition to regular physical exercise, may also prevent muscle wasting in dialysis patients. For the prevention and cure of sarcopenia and frailty, we must carry out research, including development of diagnostic methods and simple screening techniques for dialysis patients in Japan. |