| [ Summary ] |
Frailty is characterized by age-associated declines in physiologic reserves and functions across multiorgan systems, leading to increased vulnerability and adverse health outcomes, such as disability or death. In order to achieve the goal of healthy long lives for older people, it is important for all health care professionals to understand the definition, assessment and implications of frailty and to develop appropriate treatment strategies. Significant progress has recently been made in understanding the pathogenesis of frailty. However, its pathophysiology, biomarkers and appropriate treatment plans have not been completely elucidated. Assessment of frailty may also be useful for implementation of risk management plans for patients with kidney disease because frailty often accompanied chronic kidney disease. Dialysis is also associated with adverse health outcomes. Therefore, we should know the implications of frailty to improve prognoses for patients with kidney disease. |