臨牀透析 Vol.29 No.2(6)


特集名 維持透析患者の消化管疾患 ― 症状からみた傾向と対策
題名 消化管悪性腫瘍のスクリーニング
発刊年月 2013年 02月
著者 田中 健太郎 東邦大学医療センター大森病院腎センター
著者 酒井 謙 東邦大学医療センター大森病院腎センター
【 要旨 】 透析患者では悪性腫瘍の発生率が高いとされている.そのなかでも消化器悪性腫瘍の頻度は最多であり,定期的なスクリーニング検査は必須であると考えられる.胃癌に対する胃内視鏡検査,大腸癌に便潜血・腫瘍マーカー・大腸内視鏡検査が有用であると考えられる.また,透析患者に行われるスクリーニング検査は透析患者の特性を配慮して選択し,結果を判定する必要があると考えられる.
Theme Diseases of alimentary tract in maintenance dialysis patients -- tendency and management from a view point of symptomatology
Title Screening for digestive tract cancer in dialysis patients
Author Kentaro Tanaka Department of Nephrology, School of Medicine, Faculty of Medicine, Toho University Omori Medical Center
Author Ken Sakai Department of Nephrology, School of Medicine, Faculty of Medicine, Toho University Omori Medical Center
[ Summary ] Malignancy is the fourth leading cause of death in Japanese chronic dialysis patients. Those patients' lives could be saved if cancer were detected in the early stages.
Screening of dialysis patients for digestive cancer appears to be a worthwhile course of action.
Digestive tract cancer is becoming increasingly prevalent, especially, colon, liver, and stomach cancer. Screening for gastrointestinal cancer, hemoccult stool tests, abdominal ultrasound examinations, CT scans and fiberscopic inspections are fundamental tools for early detection.
Published guidelines for the treatment of HCV infection in Japanese dialysis patients are useful for treatment of HCV related liver cancer. Many tumor markers yield false-positive results in dialysis patients and should be used carefully. As dialysis patients age, increasingly higher cancer rates are observed. These factors force dialysis practitioners to confront their patients' mortality and quality of life.
戻る