| Theme |
Antiplatelet and Anticoagulation Therapy in Patients with Chronic Kidney Disease -- up to date of evidence |
| Title |
Disseminated intravascular coagulation (DIC) |
| Author |
Hideo Wada |
Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine |
| Author |
Yuji Shimokariya |
Department of Central Laboratory, Mie University Graduate School of Medicine |
| [ Summary ] |
Disseminated intravascular coagulation (DIC) may be observed in both hypercoagulable and hyperfibrinolytic states. Bleeding symptoms occur in association with hyperfibrinolytic states. Thrombotic symptoms may occur in hypercoagulable states. Three diagnostic criteria for DIC have been established by the Japanese Ministry Health and Welfare, the International Society of Thrombosis and Haemostasis, and the Japanese Association for Acute Medicine. These diagnostic criteria are scored in prothrombin times. Platelet counts, fibrinogen levels and fibrin related markers are monitored. DIC is classified as being either the "asymptomatic type", the "bleeding type", the "organ failure type" or "thrombotic complication type". Particular types of treatment for DIC are recommended for individual DIC states in consensus with the DIC treatment guidelines established by the Japanese Society of Thrombosis and Hemostasis. |