| [ Summary ] |
In recent years, a great deal of interest has been paid to CKD as one risk factor for cardiovascular disease (CVD). We assessed the usefulness of CKD and hypertension (HT) as predictors of the occurrence of CVD events in the Japanese population. The participants in this study consisted of 1,776 men and women who underwent medical examinations in the towns of Tanno and Sobetsu in Hokkaido. Participants were divided into two groups according to eGFR levels. A CKD group and a non-CKD group, and were also divided into an HT group and a non-HT group. These groups were followed up for a maximum of 8 years. The incidence of CVD was 8.3 (/ 1,000 person-year) in the normal group, 16.7 in the CKD group, 19.9 in the HT group, and 25.5 in the CKD and HT group. The survival rates were found to be significantly lower in the CKD group, the HT group, and the CKD and HT group than in the normal group. The survival rate in the CKD and HT group was the lowest among these four groups. In conclusions, both CKD and HT were independently good predictors of future occurrence of CVD. However, HT with CKD was a stronger predictor of CVD events than CKD or HT alone. |