臨牀透析 Vol.28 No.10(1-1)


特集名 CKDキャンペーンの成果と今後のCKD・透析医療
題名 CKDの診断と問題点 (1) 日本人のCKDの特徴について
発刊年月 2012年 09月
著者 井関 邦敏 琉球大学医学部附属病院血液浄化療法部
【 要旨 】 CKDステージ3が3a(eGFR 45~59 mL/min/1.73 m2)と3b(eGFR 30~44mL/min/1.73 m2)に新たに分割された.この分類に従い2008年度の特定健診受診者(n=332,174,年齢40~74 歳)のデータの解析を行った.eGFR 60 mL/min/1.73 m2 未満は全体の14.5%であった.eGFR 60 mL/min/1.73 m2以上で試験紙法1+以上の蛋白尿陽性者は3.8%であった.米国の健診受診者と比較すると,日本人のGFRは明らかに低値が多い.日本人からみると米国人は過剰濾過気味である.肥満,たんぱく質摂取量,出生時体重の相違などが考えられる.
Theme Outcomes of CKD Campaign and Future Treatments Concerning CKD and Dialysis
Title Characteristics of CKD in Japanese
Author Kunitoshi Iseki Dialysis Unit, University Hospital of the Ryukyus
[ Summary ] According to the new classification of CKD by KDIGO, stage 3 CKD should be divided into 3a (eGFR 45-59 mL/min/1.73 m2) and 3b (eGFR 30-44 mL/min/1.73 m2) categories. Among the screened subjects (N=332,174, age 40 to 74 years) enrolled in the Specific Health Check Program (known as the Tokutei-Kenshin), the prevalence of low eGFR, <60 mL/min/1.73 m2, was 14.5 %. The prevalence of dipstick positive (1+ and over) proteinuria was 3.8 %. Compared to US health check subjects Japanese subjects were found to have a distribution of lower levels of eGFR. Exact mechanisms responsible for these differences are not clear but the prevalence of obesity, protein intake and birth weight, which determine the levels of GFR, are obviously different.
戻る