臨牀透析 Vol.27 No.6(4)


特集名 透析患者の歯科領域疾患
題名 透析患者の象牙質知覚過敏症,う蝕および歯髄疾患
発刊年月 2011年 06月
著者 須田 英明 東京医科歯科大学大学院医歯学総合研究科歯髄生物学分野
【 要旨 】 透析患者は冷たいものを好むため,象牙質知覚過敏を訴えることが少なくない.象牙質知覚過敏の治療は,開口した象牙細管を封鎖するとともに,過敏化した歯髄神経の興奮を鎮静することに主眼がおかれる.象牙質知覚過敏症状が強くなると,歯髄の全摘出が必要となるので,早期治療が大切である.他方,健常者と比べ,透析患者のう蝕発生リスクが高いわけではない.むしろ,透析患者の唾液のpHは高いレベルで維持されており,う蝕が生じやすい環境にはない.このため,透析患者のう蝕罹患状況は,健常者と比べて有意差が認められないとする報告が多い.う蝕を放置すれば歯髄疾患を継発し,全身へ疾患が波及する.透析患者の免疫能低下などを勘案すると,う蝕の早期発見・治療がやはり大切である.
Theme Oral Diseases and Oral Care in Dialysis Patients
Title Dentin hypersensitivity, dental caries and pulpal diseases in dialysis patients
Author Hideaki Suda Pulp Biology and Endodontics, Department of Restorative Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
[ Summary ] Patients receiving dialysis (PRDs) frequently complain of dentin hypersensitivity (DH), which may be due to the fact that they are fond of cold foods and water. Treatment of DH is based on the occlusion of open dentinal tubules on the exposed dentin surface and sedation of sensitized tooth pulp nerves. When pain elicited by DH becomes strong, total pulp extirpation may be required. Therefore, early treatment is of prime importance for DH care. On the other hand, PRDs do not have a higher risk of dental caries. The pH of their saliva is maintained at a higher level. Hence, their oral environment is not suitable for the formation of dental caries. Many investigators have reported that there are no statistical differences between the number of dental caries observed in PRDs and healthy control groups. However, early diagnosis and treatment of dental caries are imperative for PRD treatment, due to the immuno-compromised conditions of these patients.
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