臨牀透析 Vol.27 No.1(1)


特集名 多様化する透析医療の最前線 -- 社会をどう変えるのか
題名 CKD運動の意義とCKD患者の動向
発刊年月 2011年 01月
著者 今井 圓裕 名古屋大学大学院医学系研究科腎臓内科学
著者 安田 宜成 名古屋大学大学院医学系研究科腎臓内科学
著者 松尾 清一 名古屋大学大学院医学系研究科腎臓内科学
【 要旨 】 慢性腎臓病(CKD)患者は,わが国に1,330万人存在し,腎機能低下のリスクが高いばかりでなく,心血管疾患の発症率も高い,ハイリスクの集団である.2004年にわが国で始まったCKD運動は,CKDの啓発という意味では大きな意義を上げたと思われる.今後わが国のCKD患者数は,社会の高齢化と糖尿病の増加によりさらに増加するものと予想される.また,透析患者数も当面は増加が続くと予想される.一方,現在のeGFRによる重症度分類では,必ずしもリスクの層別化が十分できてはいない.今後,CKD患者を原疾患,eGFR,尿蛋白量により層別化して,リスクの高い糖尿病性腎症,腎硬化症患者への医療資源の投資を集中的に行い,CKD患者の腎不全,心血管病への進展を効率的に抑制することが必要である.
Theme Diversified Frontier of Dialysis Therapy -- We Can Change
Title Present state of and perspectives on CKD in Japan
Author Enyu Imai Department of Nephrology, Nagoya University Graduate School of Medicine
Author Yoshinari Yasuda Department of Nephrology, Nagoya University Graduate School of Medicine
Author Seiichi Matsuo Department of Nephrology, Nagoya University Graduate School of Medicine
[ Summary ] The number of Japanese patients with chronic kidney disease (CKD) is estimated to be 13 million. CKD patients are at risk of declining renal function and concomitant comorbidity associated with cardiovascular diseases. The Japanese program for detection and classification of CKD was started by the Japanese Society of Nephrology in 2004. Public policy concerning CKD has increased awareness of CKD by medical professionals past 7 years. In spite of efforts being made through CKD initiatives, the prevalence and incidence of CKD in Japan is expected to increase over the next 10 years because of our rapidly aging population and the steadily increasing prevalence of diabetes.
Shortcomings in the present classification of CKD employing eGFR values are well recognized since amount of proteinuria is not used for CKD risk assessment. The revised KDIGO classification is two dimensional and composed of eGFR values and amounts of proteinuria. Causative disease of CKD needs to be noted. Risk assessment will be done accurately by using the new CKD classification, enabling us to treat high risk patients early on and appropriately.
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