臨牀透析 Vol.26 No.5(7)


特集名 透析患者の心臓―心臓病による死亡を減らすために
題名 透析患者の虚血性冠疾患
発刊年月 2010年 05月
著者 大坪 義彦 天神会新古賀病院循環器科
著者 古賀 伸彦 天神会新古賀病院循環器科
【 要旨 】 透析患者は種々の古典的危険因子と慢性腎臓病関連の危険因子を有し,冠疾患の合併頻度が高い.透析患者の冠疾患病変では,多枝病変や高度な石灰化病変を多く認める.冠疾患の診断に際しては,非典型的な症状や無症候性の場合があることや,心電図変化が捉えにくい場合があることに注意を要する.冠疾患の検査には,心エコー・心臓核医学検査・冠動脈CT・心臓MRIや冠動脈造影がある.冠動脈造影は,冠疾患診断においてのgold standardであるが,侵襲的検査であり,透析患者では合併症の頻度が高いことを考慮する必要がある.
Theme Heart and it's Diseases in Dialysis Patients -- For their better longevity
Title Ischemic coronary artery disease in dialysis patients
Author Yoshihiko Otsubo Tenjin-kai Shin-Koga Hospital
Author Nobuhiko Koga Tenjin-kai Shin-Koga Hospital
[ Summary ] Dialysis patients have various risk factors involving traditional factors and chronic kidney disease (CKD) related-factors. These patients also have a high prevalence of CAD (coronary artery disease). Regarding the clinical characteristics of these patients, we observed significantly high frequencies of multi-vessel lesions and the presence of severe coronary calcification. Care should be taken when diagnosing CAD in these patients because their symptoms are atypical and there are difficulties in accurately reading the changes observed in electrocardiograms. There are various techniques for diagnosing CAD, including echocardiography, nuclear cardiology, cardiac computed tomography, cardiac magnetic resonance, and coronary angiography (CAG). CAG is the gold standard for evaluating CAD, however, it is necessary to keep in mind the fact that CAG is an invasive technique and the complications associated with CAG procedures are found comparatively frequently in dialysis patients.
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