| Theme |
Re-consideration for the Modification of Hemodialysis Therapy |
| Title |
Phosphorus removal in management of mineral and bone disorders |
| Author |
Hiraku Yoshida |
Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine |
| Author |
Hiroyasu Yamamoto |
Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine |
| [ Summary ] |
Hyperphosphatemia in patients with end stage renal disease is associated with increases in all causes of mortality, including cardiovascular incidents and vascular calcification. Therapeutic strategies aimed at phosphorus control typically include restriction of dietary phosphorus intake, reducing intestinal absorption through use of phosphorus binders, and removing phosphorus with tri-weekly conventional dialysis. Despite these approaches, normalization of phosphorus levels is often difficult to achieve. Nocturnal hemodialysis and short daily hemodialysis are superior to conventional hemodialysis in terms of phosphorus removal and being able to decrease phosphorus binder dosage. |