| Theme |
Present Status of Peritoneal Dialysis in Japan |
| Title |
Low calcium dialysate and high calcium dialysate |
| Author |
Hiroyasu Yamamoto |
Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine |
| Author |
Jun Mitome |
Division of Kidney and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine |
| [ Summary ] |
Peritoneal dialysate calcium (Ca) concentrations are important in strategies for chronic kidney disease-mineral and bone disorder, because the dialysate calcium concentration influences serum calcium levels directly, and may change the dosage of phosphate binders and vitamin-D analogs. High Ca dialysates have been used to correct hypocalcemia in chronic renal failure. Low Ca dialysates were then produced to increase the dosage of Ca containing phosphate binders and vitamin-D analogs. However, there is not enough evidence to choose low Ca dialysates for peritoneal dialysis. When low Ca dialysates are employed it should be recognized that there is a risk of deteriorating secondary hyperparathyroidism. |