| Theme |
Reconsidering of Diet Therapy for Patients with Chronic Kidney Disease -- Is the clinical guideline for diet therapy edited by Japanese Society of Nephrology at 1997 valid? |
| Title |
Biochemical markers for assessment of nutritional status of chronic kidney disease |
| Author |
Takako Takita |
Department of Internal Medicine, Maruyama Hospital |
| Author |
Akihiko Kato |
Division of Blood Purification, Hamamatsu University School of Medicine |
| [ Summary ] |
Several biochemical markers such as serum albumin, prealbumin, total cholesterol and creatinine have been used for the assessment of nutritional status of chronic renal failure patients. Serum albumin levels reflect chronic changes in nutritional status, while serum prealbumin reflects shorter-term changes. These biochemical markers are known to be associated with all-cause of mortality. This is especially so in relation to serum albumin and cardiovascular events. Since malnutrition is closely related to systemic inflammation and atherosclerosis, it is necessary to conduct comprehensive biochemical assessments employing the measurement of serum C-reactive proteins. In addition, establishment of new nutritional guidelines for Japanese dialysis patients will be required to assess nutritional status more accurately. |