Theme |
The Various Uremic Symptomes and their Causative Substances |
Title |
Immunosuppression associated with end-stage renal disease |
Author |
Yoshito Naiki |
Department of Nephrology and Rheumatology, Kinki University School of Medicine |
Author |
Hirofumi Hasegawa |
Department of Nephrology and Rheumatology, Kinki University School of Medicine |
[ Summary ] |
Infectious diseases are among the events with the highest morbidity and mortality rates for dialysis patients. These infectious diseases often lead to sepsis. Uremia is associated with a state of immune dysfunction with increased susceptibility to infection. In this review, the possible influence of ureimc toxins on immune dysfunction in dialysis patients is discussed. |