臨牀透析 Vol.21 No.6(11)


特集名 透析患者の眼
題名 眼科領域における再生医学
発刊年月 2005年 06月
著者 高橋 政代 京都大学附属病院探索医療センター
【 要旨 】 眼科領域では,古くから角膜移植や人工レンズという機能再建治療が行われてきた.現在では,角膜移植も全層角膜移植,表層角膜移植のほかに角膜上皮の前駆細胞を移植する角膜上皮形成術や輪部移植が行われている.また,神経幹細胞の概念確立とともに,過去には再生しないと信じられてきた網膜の機能再建も考えられるようになった.網膜はまだ再生医療ではなく,移植細胞源の確保や移植法の確立など基礎研究の段階であるが、着実に進歩している.
Theme The Eye in Hemodialysis Patients
Title Regenerative medicine in ophthalmologic field
Author Masayo Takahashi Department of Experimental Therapeutics Translational Research Center, Kyoto University Hospital
[ Summary ] In the ophthalmologic field, functional reconstruction treatment such as corneal transplantation or artificial lens transplantation has been performed for a great deal of time. Recently corneal transplantation has become so advanced that lenticular transplantation at the limbus that supply corneal stem cells is performed as well as penetrating keratoplasty and the lamellar keratoplasty. Moreover, establishment of the concept of neural stem cells has made retinal regeneration realistic. As for the retinal transplantation, the research is still at the stage of basic research such as cell recruitment but it is progressing gradually.
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