| [ Summary ] |
Kidney transplantation is now considered as an optimal therapy for all children with end-stage renal disease, since it is the only long-term therapy that offers children with chronic renal failure the potential of a near normal life.
Recent advances in technology and immunosuppression have greatly enhanced the outlook for patients and rates of graft survival, while reducing significant complications. Future studies must be directed at allograft induction tolerance, reduction of chronic allograft nephropathy (CAN), prevention of serious infectious and neoplastic complications, as well as enhanced growth and development of the child. |