臨牀透析 Vol.21 No.10(3)


特集名 小児腎不全 -- 発見から治療まで
題名 小児における腎・尿路疾患の泌尿器科的管理
発刊年月 2005年 09月
著者 中井 秀郎 獨協医科大学越谷病院泌尿器科
著者 木原 敏晴 獨協医科大学越谷病院泌尿器科
著者 北原 聡史 獨協医科大学越谷病院泌尿器科
著者 安田 耕作 獨協医科大学越谷病院泌尿器科
【 要旨 】 小児腎不全を引き起こす病態として,腎形成不全,閉塞性腎症,逆流性腎症の三者が挙げられる.通常は先天性尿路奇形に随伴してこれらの病態が合併し,それぞれ単独あるいは複合して,腎不全発生や進行の原因となる.腎形成不全には胎児の尿路閉塞が強く関連しているが,予防方法は未確立である.閉塞性腎症では,尿路閉塞が両側性かどうか,上部・下部尿路のどちらにあるかが腎不全の発生に重要で,通常は急激に進行することが多い.一方,逆流性腎症での腎不全の進行は緩徐である.閉塞解除の意義,尿路感染予防,膀胱尿管逆流症 (VUR) 防止術の意義などを概説する.
Theme A Total Care of Renal Failure from the Onset in Children
Title Urological management of kidney and urinary tract in children
Author Hideo Nakai Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital
Author Toshiharu Kihara Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital
Author Satoshi Kitahara Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital
Author Kousaku Yasuda Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital
[ Summary ] The major predisposing factors related to pediatric renal insufficiency are basically renal hypo / dysplasia, obstructive nephropathy and reflux nephropathy. These 3 factors independently or together cause renal insufficiency in the pediatric patients. Hypo / dysplastic kidneys often result from severe urinary tract obstructions in the fetus, for which no prophylactic treatment has been established yet. In obstructive uropathy, the sites of obstruction (upper or lower urinary tract) and bilaterality are important for the development of renal insufficiency and its clinical onset is generally acute. In reflux nephropathy, the development of renal insufficiency is usually slower. In this article, the efficacy of the timely removal of obstructions and anti-bacterial chemotherapy as well as anti-reflux surgery are discussed.
戻る