| [ Summary ] |
Protein adsorption is the first phenomenon of the blood-dialyzer interaction. Protein adsorption plays a role for biocompatibility and performance of a dialyzer. Furthermore, protein adsorption is concerned for the removal of low-molecular protein. The adsorption is not dependent on the plasma concentration, but on the physical or chemical structure of the membrane and biochemical characteristics of plasma protein. The biocompatibility of the membrane may be regulated not only on the inhibition of attachment of leukocytes by adsorbed protein onto the membrane surface, but on the adsorption of some specific proteins, such as unactivated complements. |