臨牀透析 Vol.20 No.11(1)


特集名 CAPD療法の新たな展開
題名 腹膜透析の変遷と新たな展開
発刊年月 2004年 10月
著者 川口 良人 神奈川県衛生看護専門学校付属病院/東京慈恵会医科大学腎臓・高血圧内科客員教授
【 要旨 】 わが国における腹膜透析 (PD) 患者数は先進諸国の利用率より低い.その理由について考察を行った.腎機能代行治療のなかでPDの実施法について知らない腎臓医が多いからである.
最近開発された新しい透析液は腹膜機能保持に利点があると期待されているが,さらなる臨床成績の蓄積が求められている.PDのなかでもっとも重篤な合併症は被嚢性腹膜硬化症であり,この発症機序は未だ明らかではないが,臨床的観察から,リスクファクター,治療の方向づけはできつつある.
Theme New Development in CAPD Therapy
Title New directions for peritoneal dialysis
Author Yoshindo Kawaguchi Kanagawa Prefectural Hospital Affiliated with Nurses Training School / Division of Nephrology and Hypertension, Jikei University School of Medicine
[ Summary ] The rate of utilization of peritoneal dialysis (PD) in ESRD treatment is lower in Japan compared with the average in developing countries. The most important point is lack of knowledge about the advantages of the therapeutic effects of PD by nephrologists in Japan. In spite of the rapid development of instruments for PD, the development of PD solutions has been extremely as slow, and has lead to problems with peritoneal membrane conditions. Although the recent availability of new solutions is expected to have the potential to protect or delay membrane damage, long-term clinical studies are required. The most serious complication with PD has been encapsulating peritoneal sclerosis. In spite of an incomplete understanding of the pathophysiological mechanisms of this state of morbidity, several risk factors and therapeutic strategies have been drawn from clinical observations.
戻る