| [ Summary ] |
Two types of continuous regeneration systems for peritoneal dialysate have been developed to enhance the solute removal efficiency in conventional peritoneal dialysis therapy, such as CAPD. In continuous recirculating peritoneal dialysis (CRPD), part of the dialysate in the patient's peritoneal cavity continuously extracorporates through a newly developed double-lumen catheter and is purified by an outside dialyzer. In bi-directional peritoneal dialysis (BPD), part of the dialysate moves back and forth between the patient's peritoneal cavity and an outside dialysate reservoir via a reversible pump, giving the system an alternating drain phase and an infusion phase. In both phases, the additional dialyzer continually purifies the peritoneal dialysate. Higher solute removal efficiency of CRPD/BPD was verified during a canine ex vivo study and a clinical study. In CRPD/BPD, there are some advantages to CAPD such as the usage of bicarbonate diffusers from outside the dialysate via added dialyzer. There was no leakage of albumin using the additional dialyzer, etc. |