| [ Summary ] |
In blood purification therapies such as hemodialysis treatments, the quantity of solute removal cannot be measured in real-time. It is thought of as a "black-box" type therapy. In order to achieve adequate treatment for each patient, we should utilize a kinetic modeling strategy. Therefore, the relationship between operating conditions, such as blood flow rates, dialysate flow rates, effective membrane surface area, treatment time, etc., and solute removal efficiency can be estimated through kinetic modeling. There are, however, some problems with kinetic modeling based on common assumptions. We should take care to appropriately utilize models for clinical applications as mentioned in this paper. |