| [ Summary ] |
One hundred seventy five hemodialysis patients received influenza vaccinations. In 43 of these patients, the level of hemagglutinin inhibitory antibody (HI) titer was above the 40 dilution titer, safety level for influenza infection. Those who could not get the safety level of serum HI with the 1st vaccination were able to achive it, after 2nd vaccination in the 80-90 percent of cases. The HI titer level for the group after 2nd vaccination was lower than for the 1st one. The average and middle titer levels were half of those seen in the initially the vaccinated group. In elder patients above 60 years of age, the safe titer level group included those in the 2nd vaccinated group. There was not a significant difference in the group under age 60, but percentage was lower than in the younger group with the 1st vaccination. Those patients who could not achive safe titer levels were recommended for administration of neuraminidase inhibiters and or amantadine. |