臨牀透析 Vol.17 No.6(4)


特集名 腎不全における悪性腫瘍
題名 ACDKと腎癌
発刊年月 2001年 06月
著者 石川 勲 金沢医科大学腎臓内科
【 要旨 】 1)慢性腎不全患者や透析患者にみられる悪性腫瘍のなかで腎癌は一般人と比べ,その発生頻度が高い.また透析患者の腎癌はその80%が嚢胞(ACDK)と関連したもので,この嚢胞は腎尿細管より発生し増殖して,癌化すると考えられる.したがって,長期透析ほど腎癌は増加する.
2)透析患者の腎癌は頻度が高く症状がないので,とくにリスクの高い人には定期的なスクリーニングが大切である.
3)スクリーニングで内部エコーのある腫瘤や,実質と等吸収値を示す腫瘤が見出されたら,なんらかの方法でそこに血流があることを証明し,手術するのが望まれる.
Theme Malignancy in Chronic Renal Failure
Title ACDK and renal cell carcinoma
Author Isao Ishikawa Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University
[ Summary ] 1) The incidence of renal cell carcinoma is high in patients with chronic renal failure and also in dialysis patients, compared to the general population. The 80% of renal cell carcinomas in dialysis patients were related to acquired renal cysts (ACDK). The reason why the incidence of renal cell carcinoma is high in dialysis patients, is that renal cell carcinoma develops in relation to ACDK. There is a close relationship between renal cell carcinoma and ACDK: renal cysts derive from the renal tubules, cystic epithelial cells proliferate, and renal cell carcinomas also develop. Accordingly, renal cell carcinoma increases in long-term dialysis patients.
2) Because of the incidence of renal cell carcinoma in dialysis patients is high and there are no symptoms, screening is important, especially for high risk patients.
3) If an echogenic mass, found through ultrasonic examination or a mass with a parenchymal absorption value is found with CT scanning blood flow inside the tumor should be proven by any method possible before an operation is performed.
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