| [ Summary ] |
Not only does Kt/V not represent an accurate level of dialysis dosage, but it is not reliable as a predictor of mortality either. According to the statistics demonstated by the Japanese Society for Dialysis Therapy, serum creatinine and creatinine generation rates greatly affect mortality, and are highly reliable as its predictive indices. This information represents muscle mass, in other words, nutritional status, and demonstrates that restraint of protein energy malnutrition (PEM) improves the prognosis for hemodialysis patients. Long term dialysis treatment with the dialysis prescription using the same membrane results in malnutrition followed by decreased solute removal. Based upon the decrease in dialysis dosage, dialysis prescriptions should be changed, that is to say, other biocompartible high-flux membranes. and endotoxin-free dialysate ought to be applied. This procedure which improves nutritional status is believed to provide a high quality of life for patients. |