Theme |
Monitoring Technologies in Dialysis Therapy |
Title |
Development of a creatinine monitoring system in the effluent dialysate |
Author |
Hideo Ebisawa |
Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University |
Author |
Jun Murakami |
Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University |
Author |
Iwakazu Kaneko |
Department of Clinical Engineering, Kidney Center, Tokyo Women's Medical University |
Author |
Michio Mineshima |
Department of Surgery III, Kidney Center, Tokyo Women's Medical University |
Author |
Tetsuzo Agishi |
Department of Surgery III, Kidney Center, Tokyo Women's Medical University |
[ Summary ] |
A creatinine monitor has recently been introduced in order to establish optimal treatment for each patient. This monitor is based on a colorimetric method, using picric acid. The value of absorbance of the creatinine solution, involving picric acid, gradually increased and reached a maximum value 15 min after the introduction of picric acid to the sample of effluent dialysate. A favorable correlation between the maximum value and the estimated value from the absorbance data was obtained in 5 min. The creatinine monitoring system is thought to be useful for the establishment of adequate dialysis for each patient, especially in home hemodialysis. |