臨牀透析 Vol.15 No.13(8-2)


特集名 腎疾患の栄養とその実際
題名 腎移植前後の栄養管理 (2) 小児
発刊年月 1999年 12月
著者 相川 厚 東邦大学医学部腎臓学教室
著者 本間 清貴 東邦大学医学部附属大森病院栄養部
【 要旨 】 本邦の成人の透析は血液透析が多いが,腎不全患児の透析は腹膜透析が主体である. 小児腎移植前の栄養管理では,運動量が少なく腹膜透析では糖が腹膜から吸収されるため年齢相当の熱量の90%が必要であり,蛋白は腹水へ喪失されるため,蛋白熱量比で13~15%が妥当である.食塩は原則的に制限はないが,高血圧,浮腫,胸水貯留,溢水がある場合は制限し,CAPDではNaが喪失されるためむしろ補給する場合がある.移植後は遅れた成長を取り戻すため年齢相当の熱量を摂取させる.蛋白や食塩の制限はないが,ステロイド,タクロリムス,シクロスポリンによる高血糖が出現する場合は過量の糖摂取は控えたほうがよい.症例7歳の移植前栄養管理は熱量1,400~1,500kcal,蛋白質55~60g(熱量比15%),脂質50g(熱量比25~27%),糖質(熱量比50~55%),食塩6g,移植後は熱量1,800~1,900kcal,蛋白質73~77g(熱量比20%),脂質64~75g(熱量比20%),糖質(熱量比60%),食塩7~9gで行い良好に経過した.
Theme Practicing proper nutrition for kidney diseases
Title Management of nutrition before and after renal transplantation
Author Atsushi Aikawa Department of Nephrology, Toho University School of Medicine
Author Kiyotaka Honma Department of Diet and Nutrition, Toho University Omori Hospital
[ Summary ] Pediatric patients with end stage renal failure are usually treated with peritoneal dialysis (PD). Therefore, total calorie intake should be restricted to 90% of normal for that age matching calorie under management of nutrition before renal transplantation regarding absorption of sugar by PD. Protein intake is not eliminated but adjusted to 13 to 15% of the protein/calorie ratio, because it is lost in the PD fluid. Sodium is not restricted except cases of hypertension, edema, fluid collection in the chest or overhydration. In contrast sodium chloride could be given orally to patients with continuous ambulatory PD (CAPD), where sodium is being excreted. In post-transplant nutrition management, total calorie intake should be adequate to re-establish normal growth patterns without any dietary control. However too much sugar intake may evoke a diabetic state, accompanied with the side-effects of steroid administration, tacrolimus or ciclosporin and excess intake of fat and cholesterol may induce obesity and damage the femoral head or knee joints. In the case of 7 years old girl, her pre-transplant daily diet consisted of a total calorie intake of 1400-1500 kcal, while protein intake was 55-60g (a protein/calorie ratio of 15%), fat 50g (the fat/calorie ratio was 25-27%), sugar (the sugar/calorie ratio was 50-55%), and NaCl of 6g. The post-transplant diet was supplied with an 1800 to 1900 kcal total, with a protein intake of 73-77g (protein/calorie ratio of 20%), fat 64-75g (fat/calorie ratio of 20%), sugar (sugar/calorie ratio of 60%) and NaCl 7 to 9g. The patient was able to receive relatively well controlled nutrition, both before and after transplantation.
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