| [ Summary ] |
A low protein diet (LPD) has been used for uremic patients since the last century. However, it was not until1 963 that LPD was fully supplemented with essential amino-acids and caloric needs were first considered. While LPD was used to relieve symptoms of uremia until 1975, it was used to slow therate of progression of renal failure after that. For nephrotic syndrome, LPD has been used before 1917, when Epstein broke with tradition and introduced a high-protein diet (HPD). In 1986, the harmful effects of HPD on glomerular function were revealed, and LPD was revived with as light degree of protein restriction. Since protein intake has a great deal of effect on renal function, many problems relating to protein intake still remain to be solved. |