| Theme |
Pathophysiology and Treatment of Deranged Lipid Metabolism in Chronic Renal Failure |
| Title |
Pharmacological approach to plasma lipoprotein level-abnormalities in hemodialysis patients |
| Author |
Tetsuo Shoji |
Second Department of Internal Medicine, Osaka City University Medical School |
| Author |
Yoshiki Nishizawa |
Second Department of Internal Medicine, Osaka City University Medical School |
| [ Summary ] |
This article reviews abnormalities of lipoprotein levels in hemodialysis patients and possible pharmacological approaches to treatment. Because some drugs are cleared through the kidney, drug accumulation limits the usefulness of most of fibric acids, except clinofibrate. Statins and nicotinic acids may be safely used. No statistics are available which show the beneficial effects of lipid lowering intervention on atherosclerosis in this population. |