| Theme |
Functional and Organic Changes of Brain Observed in Dialysis Patients |
| Title |
Cerebrovascular rheology with reference to blood cell components |
| Author |
Hideyuki Niimi |
Department of Microcirculatory Science, National Cardiovascular Center Research Institute |
| Author |
Takashi Yamakawa |
Department of Microcirculatory Science, National Cardiovascular Center Research Institute |
| [ Summary ] |
Cerebral blood flow is governed by perfusion pressure and vascular resistance. The latter factor may be influenced by the geometry (or topology) of microvessels as well as the rheological property of blood. Cerebral blood flow may be regulated by changing microvascular resistance, which includes both the flow and the deformation of blood cells (erythrocyte and leukocyte) and the mechanical response of endothelial cells to blood flow. This review focuses on rheological factors which influence cerebral blood flow. |