| [ Summary ] |
The mechanisms by which blood pressure is elevated in patients with end-stage renal failure is related to numerous factors. One is reduction of the glomerular filtration fraction.Reduction of GFR elevated blood pressure, thereby leading to sodium accumulation.Accumulation of sodium elevates blood pressure according to Guyton's theory. To interrupt this sequence of causes and consequences,sodium restricted foodi sprovided. However, since too rapidly restricting sodium often exaggerates GFR, mild introduction of salt restriction is much better. In addition to salt restriction, antihypertensive therapy is important for preventing the acceleration of blood pressure elevation. Acombination of calcium antagonists and ACE inhibitors may be the treatment of choice. |