INTESTINE Vol.9 No.6(2-1-1)

特集名 大腸ポリポーシスと関連疾患 (遺伝性大腸癌)
題名 ポリボーシス (1) 家族性大腸腺腫症 a. 診断
発刊年月 2005年 11月
著者 岩間 毅夫 佐々木研究所附属杏雲堂病院外科
【 要旨 】 要旨はありません。
Theme Polyposis of the colon and rectum, and other related conditions : hereditary colorectal cancer
Title Familial adenomatous polyposis
Author Takeo Iwama Department of Surgery, Kyoundo Hospital, Sasaki Foundation
[ Summary ] Points for diagnosing familial adenomatous polyposis (FAP) were described. Early diagnosis before the development of invasive colorectal cancer was stressed. For that purpose, family history taking and early diagnosis are essential procedures. The criteria for diagnosis were proposed. We described several patterns in the producion of adenomatous polyposis, from the diffuse type to those with sparse distribution. Recently, a new type of adenomatous polyposis of the colon has been categorized. It is caused by a defect in the MYH gene, and is inherited in an autosomal recessive manner. Care and treatment of MYH, associated polyposis, were recommended following the concepts of treatment for FAP.