INTESTINE Vol.9 No.2(5-2)


特集名 拡大内視鏡の最前線
題名 炎症性腸疾患に対する拡大内視鏡の意義 (2) Dysplasia (DALM) に対する意義
発刊年月 2005年 03月
著者 五十嵐 正広 北里大学東病院消化器内科
著者 佐田 美和 北里大学東病院消化器内科
著者 小林 清典 北里大学東病院消化器内科
著者 吉澤 繁 北里大学東病院消化器内科
著者 勝又 伴栄 北里大学東病院消化器内科
【 要旨 】 要旨はありません。
Theme The front line of magnifying endoscopy and pit pattern diagnosis -- Now and future
Title Significance of magnifying observation of DALM
Author Masahiro Igarashi Department of Gastroenterology, Kitasato University East Hospital
Author Miwa Sada Department of Gastroenterology, Kitasato University East Hospital
Author Kiyonori Kobayashi Department of Gastroenterology, Kitasato University East Hospital
Author Shigeru Yoshizawa Department of Gastroenterology, Kitasato University East Hospital
Author Tomoe Katsumata Department of Gastroenterology, Kitasato University East Hospital
[ Summary ] We reviewed the significance of magnifyied observation of DALM for 14 patients (19 lesions) who were observed with magnifying colonoscopy. The frequency of DALM was discovered in 11 cases (12.5 %) of extensive colitis (88 patients) and in 3 cases (6.5 %) of left sided colitis (46 patients) that we performed surveillance colonoscopy on. The average age of patients with DALM was 54.8 ± 16.2 years old and the average morbidity period was 13.7 ± 6.6 years. DALM was located in 95 % of the cases in the rectum and the sigmoid colon. The macroscopic type of Nagasako classification of DALM indicated the superficial elevated type -- 53 %, the nodule -- aggregating type -- 26 %, the sessile type -- 11 % and the depressed type -- 5 %, respectively. Discovery of elevated lesions with DALM were not so difficult to observe, however, superficial elevated lesions or flat lesions were difficult without using the dye spraying method. Using magnifying observation was useful to diagnose dysplasia, which was revealed in patterns and which resembled neoplastic pit patterns. On the other hand, differential diagnosis with sporadic adenoma and dysplasia was difficult using only magnifying views.
It is concluded that magnifying observation with dye spraying is the most efficient method of diagnosis for ulcerative colitis associated with dysplasia.
戻る