| Theme |
Recent advances in the diagnostic imaging and the treatment of liver metastates from colorectal cancer |
| Title |
Local ablation therapy for liver metastasis from colorectal cancer -- Radio-frequency ablation (RFA) in comparison with microwave coagulation therapy (MCT) |
| Author |
Toru Beppu |
Department of Surgery II, Kumamoto University Medical School |
| Author |
Koichi Doi |
Department of Surgery II, Kumamoto University Medical School |
| Author |
Takatoshi Ishiko |
Department of Surgery II, Kumamoto University Medical School |
| Author |
Hiroshi Egami |
Department of Surgery II, Kumamoto University Medical School |
| Author |
Michio Ogawa |
Department of Surgery II, Kumamoto University Medical School |
| [ Summary ] |
We used a new locoregional ablation therapy on 40 patients with liver metastasis from colorectal cancer. Local ablations were performed with radio frequency ablation (RFA) and/or microwave coagulation therapy (MCT). Ablation therapies were performed with percutaneous, endoscopic and operative techniques. RFA, in combination with MCT, is useful for large tumors located near the surface of the liver. The regional recurrence rate at the therapeutic sites was 15% (median follow-up period 2.5 years). The cumulative survival rates over a five years period were 37% for local ablation, 41% for hepatic resection and 5% for regional chemotherapy, respectively. Complications were encountered in only two patients (one biliary fistula and one liver abscess). Local ablation therapy is a radical and safe locoregional treatment, which can provide long range survival. |