| Theme |
Recent advance in diagnosis and management of colorectal tumors associated with inflammatory bowel disease |
| Title |
Diagnosis of invasion depth of ulcerative colitisrelated colorectal tumors |
| Author |
Kiyonori Kobayashi |
Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine |
| Author |
Tomoya Saitou |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Yasuhiro Matsumoto |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Kana Kawagishi |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Miyuki Mukae |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Kaoru Yokoyama |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Miwa Sada |
Department of Gastroenterology, Kitasato University School of Medicine |
| Author |
Wasaburo Koizumi |
Department of Gastroenterology, Kitasato University School of Medicine |
| [ Summary ] |
Diagnosis of invasion depth of ulcerative colitis (UC)-related tumors with endoscopic examination, presenting cases we have experienced are illustrated. UC-related tumors are affected by factors such as chronic inflammation associated with UC and regenerative changes. Moreover, such tumors include high incidences of poorly differentiated adenocarcinoma and mucinous carcinoma. Differentiated adenocarcinomas often invade deeply while retaining the characteristics of mucosal lesions, making it difficult to estimate the depth of invasion on the basis of changes in the surface structure of the tumor. Conventional techniques for endoscopic diagnosis thus often cannot be used. Because endoscopic ultrasonography can depict tomographic images of tumors it is expected to be useful for diagnosis the depth of invasion of colitic cancer. Endoscopic diagnosis of invasion depth of UC-related tumors may requires the establishment of different diagnostic techniques than those used to diagnose conventional colorectal carcinomas. Analyses of large numbers of cases are thus required. |