INTESTINE Vol.21 No.6(2-11)


特集名 小腸の炎症性病変を見直す
題名 各論(11)ANCA関連血管炎の小腸病変
発刊年月 2017年 11月
著者 鳥巣 剛弘 九州大学大学院医学研究院病態機能内科学
著者 岡本 康治 九州大学大学院医学研究院病態機能内科学
著者 梅野 淳嗣 九州大学大学院医学研究院病態機能内科学
著者 永田 豊 九州大学大学院医学研究院病態機能内科学
著者 原田 英 九州大学大学院医学研究院病態機能内科学
著者 澤野 美由紀 九州大学大学院医学研究院病態機能内科学
著者 江﨑 幹宏 九州大学大学院医学研究院病態機能内科学
【 要旨 】 ANCA関連血管炎に分類される好酸球性多発血管炎性肉芽腫症,多発血管炎性肉芽腫症,顕微鏡的多発血管炎を中心に概説した.ANCA関連血管炎は全身性に細小動脈を中心とした血管炎を生じ,多彩な臨床徴候を呈するまれな疾患である.これらの疾患は小腸を中心に消化管病変が出現する場合があり,時に腸管穿孔や出血などの重篤な合併症をきたし予後規定因子となりうる.よって,ANCA関連血管炎の消化管病変の特徴を把握しておく必要がある.
Theme Reviewing inflammatory diseases of small bowel
Title Intestinal involvement in ANCA-associated vasculitis
Author Takehiro Torisu Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Yasuharu Okamoto Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Junji Umeno Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Yutaka Nagata Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Akira Harada Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Miyuki Sawano Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
Author Motohiro Esaki Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
[ Summary ] Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, including eosinophilic granulomatosis with polyangiitis, granulomatosis with polyangiitis, and microscopic polyangiitis are summarized. ANCA-associated vasculitis is a form of necrotizing vasculitis, predominantly affecting small vessels. ANCA-associated vasculitis affects the whole body and may involve the gastrointestinal (GI) tract in some patients. Since GI bleeding and perforations affect prognoses, it is important to know the features and degree of GI involvement in ANCA-associated vasculitis.
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