| Theme |
New evolvement in treatment for early rectal cancer |
| Title |
Characteristics of T1 rectal cancer -- in comparison with T1 colon cancer |
| Author |
Takuya Hombu |
Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East |
| Author |
Yusuke Yoda |
Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East |
| Author |
Hiroaki Ikematsu |
Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East |
| [ Summary ] |
In the patients with submucosal (T1) colorectal cancer treated in accordance with the Japanese guideline, long-term outcomes were good. Recently, expansion of the indication for endoscopic treatment of T1 cancer have been discussed. However, the risk of local recurrence was significantly higher in the patients with high-risk T1 rectal cancer than in those with T1 colon cancer treated with only endoscopic resection. Currently, the addition of surgery is recommended for patients with high-risk T1 rectal cancer that indicates a high risk of tumor progression. However, rectal surgery is more invasive than colonic surgery. Thus, a few patients refused surgery in view of quality of life. Development of a new treatment will be an urgent need in the future to reduce the recurrence rate while preserving the anatomy and function of the anus. |