| Theme |
Current topics in interval colorectal cancers |
| Title |
Interval cancer in view of the Japan Polyp Study |
| Author |
Takahisa Matsuda |
Cancer Screening Center/Endoscopy Division, National Cancer Center Hospital |
| Author |
Yasushi Sano |
Sano Hospital |
| Author |
Takahiro Fujii |
TF Clinic |
| Author |
the Japan Polyp Study Workgroup |
the Japan Polyp Study Workgroup |
| [ Summary ] |
It has been established that total colonoscopies (TCS) can reduce colorectal cancer mortality based on the results of several case-control/cohort studies. However, some authors have reported that the effects are less notable in the proximal colon than in the distal colon. Recently, interval cancer/post-colonoscopy colorectal cancer has attracted attention as an important cause of this condition. We assess the incidence and characteristics of lesions detected by TCS one-year after declaration of a "clean colon" based on the results of the Japan Polyp Study (JPS). As a result, it is suggested that overlooking nonpolypoid lesions, primarily LST-NG, in the proximal colon and small polypoid lesions in the distal colon may be the greatest causes of interval cancers. |