| Theme |
Intestinal inflammation in small bowel |
| Title |
Eosinophilic gastroenteritis |
| Author |
Tomohiko Moriyama |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author |
Motohiro Esaki |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author |
Koichi Kurahara |
Institute of Gastroenterology, Matsuyama Red Cross Hospital |
| Author |
Takayuki Matsumoto |
Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University |
| [ Summary ] |
While a diagnosis of eosinophilic gastroenteritis (EGE) was made on the basis of the Western criteria, novel diagnostic criteria based on the analysis of Japanese patients have recently been proposed. There are no endoscopic or radiographic findings of the small intestine which are specific to EGE. To diagnose EGE, it is necessary to obtain biopsy specimens from mucosa which is normal in appearance. Corticosteroids are generally efficacious for treating EGE patients. Genetic screening, functional analysis of lymphocytes, and bone marrow biopsies are required for EGE patients with hypereosinophilia, steroid-dependence, or steroid resistance. |