| Theme |
Intestinal inflammation in small bowel |
| Title |
Chronic inflammatory bowel diseases of unknown etiology -- chronic nonspecific multiple ulcers of the small intestine and other (chronic inflammatory bowel disease of unknown etiology) |
| Author |
Shigeyoshi Yasukawa |
Department of Gastroenterolog, Fukuoka University Chikushi Hospital |
| Author |
Fumihito Hirai |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Noritaka Takatsu |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Yutaka Yano |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Takashi Nagahama |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Takashi Hisabe |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Toshiyuki Matsui |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Keisuke Ikeda |
Department of Pathology, Fukuoka University Chikushi Hospital |
| Author |
Akinori Iwashita |
Department of Pathology, Fukuoka University Chikushi Hospital |
| [ Summary ] |
Chronic inflammatory bowel diseases of unknown etiology, other than Crohn's disease, Behçet's disease, simple ulcers, non-specific multiple ulcers of the small intestine and diffuse small intestinal lesions associated with Satoyoshi syndrome are examined in relation to a case encountered in our hospital. The clinical presentation of non-specific multiple ulcers of the small intestine is characterized by a persistent positive result on fecal occult blood tests, as well as iron-deficiency anemia and hypoproteinemia begining at an early age. These lesions commonly occur in the middle to lower small intestine, excluding the terminal ileum and are associated with shallow ulcers of annular to oblique shape. Generally normal intervening mucosae are also present. This is a rare disease, with a characteristic course and findings. Recognition of these symptoms is important for diagnosis. Satoyoshi syndrome is primarily characterized by symptoms including progressive muscle spasms, alopecia universalis, and diarrhea. In this case, diffuse small intestinal lesions were observed, with characteristics of a rough mucosal surface and granular elevations of various sizes. Satoyoshi syndrome has traditionally been considered a neurological disease, but the presence of intestinal lesions associated with this syndrome have recently been observed. |