INTESTINE Vol.16 No.5(3-2)


特集名 血管関連の潰瘍性腸病変
題名 急性腸管虚血 (2) 非閉塞性腸間膜虚血
発刊年月 2012年 09月
著者 板橋 道朗 東京女子医科大学第二外科
著者 大塚 亮 東京女子医科大学第二外科
著者 竹本 香織 東京女子医科大学第二外科
著者 亀岡 信悟 東京女子医科大学第二外科
【 要旨 】 非閉塞性腸間膜虚血(non-occlusive mesenteric ischemia;NOMI)は,急性腸管虚血の20〜30%を占めきわめて予後不良である.虚血は広い領域に非連続的に分節状に発生する.NOMIは特異的症状に乏しい.本症を念頭に診断することが重要である.造影CTと血管造影が有用であり,経カテーテル的に薬剤投与を行うが,軽快しない場合には,躊躇せず手術を行う.NOMIの救命率向上のためには,腸管に不可逆的な腸管壊死が起きる前の早期診断と早期の治療開始が重要である.
Theme Intestinal ulcerations related to vascular disorders
Title Non-occlusive mesenteric ischemia ; NOMI
Author Michio Itabashi Department of Surgery 2, Tokyo Women's Medical University
Author Ryo Otsuka Department of Surgery 2, Tokyo Women's Medical University
Author Kaori Takemoto Department of Surgery 2, Tokyo Women's Medical University
Author Shingo Kameoka Department of Surgery 2, Tokyo Women's Medical University
[ Summary ] Non-occlusive mesenteric ischemia (NOMI) accounts for 20-30 % of all cases of acute mesenteric ischemia (AMI). Clinical signs of NOMI are non-specific. Early symptoms are frequently absent so that acute abdominal pain may be the only presenting symptom of mesenteric ischemia. Blood markers are also non-specific and only helpful in providing subsequent therapy. NOMI is a condition characterized by high mortality rates. These poor outcomes are associated with perioperative circulatory shock, receiving adrenergic agents, and massive bowel necrosis. To improve the dismal results for nonocclusive mesenteric ischemia, recognition of patients at high risk, early diagnosis using computed tomography, and treatment with vasodilators and minimizing bowel resection are essential.
戻る