| Theme |
Intestinal ulcerations related to vascular disorders |
| Title |
Intestinal manifestations in systemic lupus erythematosus |
| Author |
Yuji Maehata |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author |
Koichi Asano |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author |
Motohiro Esaki |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author |
Takayuki Matsumoto |
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| [ Summary ] |
Gastrointestinal symptoms are common in systemic lupus erythematosu (SLE). Intestinal lesions are classified into lupus enteritis (multiple ulcer type and ischemic enteritis type) and protein-losing gastroenteropathy. In the multiple ulcer type, punched-out ulcers are found in the distal colon. In contrast, the ischemic enteritis type is characterized by diffuse submucosal edema in the small intestine. Protein-losing gastroenteropathy results in hypoproteinemia. Steroid therapy is effective for the ischemic enteritis type and protein-losing gasroenteropathy. However, the multiple ulcer type is intractable to medication, and it often causes intestinal perforations. |