Theme |
Recent trend in infectious diseases of the intestine |
Title |
Cytomegalovirus enterocolitis |
Author |
Yosuke Abe |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Mitsuyuki Murano |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Naoko Murano |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Eijiro Morita |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Ken Kawakami |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Kumi Ishida |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Takanori Kuramoto |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Ken Narabayashi |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Eiji Umegaki |
2nd Department of Internal Medicine, Osaka Medical College |
Author |
Kazuhide Higuchi |
2nd Department of Internal Medicine, Osaka Medical College |
[ Summary ] |
Cytomegalovirus (CMV) enterocolitis often develops as an opportunistic infection in immunocompromised patients who have received corticosteroids, immunomodulators, anti-cancer drugs or have underlying diseases associated with AIDS, malignant tumors, organ transplants, or autoimmune disease. Its onset presents some typical symptoms, including diarrhea, abdominal pain, or hematochezia. It is likely to lead to massive bleeding and perforations, especially small bowel lesions. It is very important to acquire knowledge of clinical courses, features of endoscopic findings, and definitive diagnostic methods, because there are various endoscopic images possible and many overlapping factors which may contribute to differential diagnosis. Colonoscopy is an extremely useful inspection tool which can help determine pathological conditions and exhibit histological findings. Therefore, colonoscopy and histologic examinations are necessary when the patient's general condition permits. |