INTESTINE Vol.14 No.2(3-5)


特集名 大腸ESDとEMRのすみ分け
題名 EMRの必要性と手技のコツ/ピットフォール (5) 辺縁切開EMR,ESD併用EMR
発刊年月 2010年 03月
著者 小泉 浩一 がん・感染症センター都立駒込病院内視鏡科
著者 服部 公昭 がん・感染症センター都立駒込病院消化器内科
著者 桑田 剛 がん・感染症センター都立駒込病院消化器内科
著者 來間 佐和子 がん・感染症センター都立駒込病院消化器内科
著者 堀口 慎一郎 がん・感染症センター都立駒込病院病理科
【 要旨 】 通常のEMRで一括切除困難な大腸表面型病変や隆起性病変に対し,病変周囲の粘膜を切開した後にスネア絞扼切除する辺縁切開EMRで一括切除できることがある.比較的短時間で施行可能で,偶発症のリスクも低く,通常EMRとESDの間に位置づけられる手技である.大きさ25mm程度までの軽度の線維化をもつ病変に対応できるが限界はあり,適応を十分に検討したうえで慎重に施行する必要がある.
Theme Selection of the therapeutic methods (EMR or ESD) for colorectal tumor
Title Hybrid EMR/ESD treatment for colorectal neoplasia
Author Koichi Koizumi Department of Endoscopy, Tokyo Metropolitan Cancer and Infection Disease Center Komagome Hospital
Author Kimiaki Hattori Department of Gastroenterology, Tokyo Metropolitan Cancer and Infection Disease Center Komagome Hospital
Author Go Kuwata Department of Gastroenterology, Tokyo Metropolitan Cancer and Infection Disease Center Komagome Hospital
Author Sawako Kuruma Department of Gastroenterology, Tokyo Metropolitan Cancer and Infection Disease Center Komagome Hospital
Author Shinichiro Horiguchi Department of Pathology, Tokyo Metropolitan Cancer and Infection Disease Center Komagome Hospital
[ Summary ] EMR is an effective treatment for broad based lesions of colorectal mucosal or slight submucosal invasive neoplasia. If submucosal injection produces bulges in lesions resembling a dome, EMR may be used as a quick, safe treatment. However, lesions with submucosal fibrosis, are not completely elevated in many cases. These lesions, which may invade the submucosal layer, are often difficult to remove with en block resection employing conventional EMR. Endoscopic submucosal dissection (ESD) seems to be more effective than EMR for curative resection. However, ESD is technically difficult, hazardous, and time consuming. Hybrid EMR/ESD, or EMR after incision of the mucosa outside of the lesion, is suitable for treatment of lesions with slight fibrosis, or lesions which have developed from IBD, with diameters of less than 25 mm. This procedure is also suitable for lesions, located on or behind folds, which are not come entirely visable.
戻る